In a huge blow to the industry, closing the doors could lead to many not reopening.

Solace Beauty owner Kim Salmi said she held "grave concerns" for the industry.

"Talking with my networks in other parts of the state, there are predictions 30-40 per cent of beauty salons in Victoria won't recover and will not reopen," she said.

"I've been very open with my team and doing everything I can to make sure that won't happen to us.

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"But it's always a possibility. When I look at the numbers - we've made a loss.

"We're an established business. We got over that seven year period and we're really confident in the direction the business was going and felt comfortable.

"This has just pulled the rug out from under us a bit. Just because we've been around for almost 10 years doesn't mean we will survive."

When Victorian Premier Daniel Andrews announced regional Victoria would enter back into stage three restrictions, Mrs Salmi said she burst into tears.

"I didn't think it would upset me as much as it did," she said.

"I was sitting with my kids watching the press conference and had a real overwhelming sense of sadness and felt deflated.

"Although I felt like that yesterday, I am feeling much better today (Monday). I think it's just the emotional roller coaster we all feel like we are on right now."

Mrs Salmi said she believed the feelings come from a combination of being responsible for a business, clients and staff.

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"We all will be going through different processes and thoughts from business owners to workers," she said.

"The first shutdown was so stressful because it was all new and we didn't know what was going to happen.

"There was no end date and my biggest concern was the payment of staff."

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Mrs Salmi said she was able to obtain JobKeeper for her staff, but it wasn't an easy system to navigate.

"Once that finally went through I was a lot better off during the first time around," she said.

"When we reopened we were really busy the first three weeks and then in certainly dropped off again in the month to follow. It was just starting to get some momentum back and now we're heading into another shutdown.

"It's worrying. I'm concerned I won't be eligible for JobKeeper this time around because of the criteria.

"We're still trying to play catch up from the last stand down."

Mrs Salmi said her business, like many others, was still tracking at a loss for the calendar year.

"There were so many costs associated with reopening after the first stand down," she said.

"There was a lot more PPE we had to buy including investing in signage and more cleaning equipment.

"A massive cost comes to having to leave time between each client to do a good clean of the room.

"We lost about 3-4 a day per therapist where we can't do treatments. We're probably sitting at about 60-70 per cent of where we were before the coronavirus pandemic."

Mrs Salmi said she would re-commence selling treatments her clients can do at home.

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"We will just be working the next three days and have the rest of the week off to gather our thoughts," she said.

"I'm finding out some clarity around if we can open for retail for click and collect and we'll continue to do that as well as home deliveries.

"Our social media was a really useful tool for us during the last shut down so we'll head back to the drawing board and think of some ways we can still connect with our clients."

Owners of new beauty business Tanyuk Collective are also feeling the impacts of what the latest restrictions could mean to their business, which open its doors three weeks ago.

"We joked about the possibility next week in a conversation," owner Ashlea Wilson said.

"I don't think anyone was expecting a six week minimum shutdown.

"I think that is what has hit me the most. For me, it's not just six weeks with no work I also have another two weeks of holidays with the kids at home."

Ms Wilson said when Tanyuk Collective was created, negotiations were made with the real estate and landlord in case of another shutdown.

"We are working through that today and see where we can save some money while there is no money coming in," she said.

"We just have to power through and rely on the government income which we will receive.

"The bills will still come in and it's just about making sure we're in a position to hopefully get back to where we want to be.

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"I've been playing catch up in March in terms of bills and trying to manage everything since the first shutdown.

"We'll get there - we've just got to ride out this wave."

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