UPDATE: The Department of Transport have issued a transport alert to motors travelling near the crash site.
Horsham-Noradjuha Road is closed in both directions between Carmichaels Road and Three Bridges Road following a truck rollover.
Motorists should use Hamilton-Natimuk Road or the Henty Highway to avoid the closure, allowing extra time for their journey.
The scene is under the control of emergency services. Horsham-Noradjuha Road will open as soon as it is safe to do so.
EARLIER: Emergency crews are on the scene after a truck has rolled over on the Horsham-Noradjuha road, about 15km south-west of Horsham.
The Wimmera Mail-Times understands about 200-300 sheep were on the truck.
Police, SES, Ambulance, and CFA are all in attendance. VicEmergency website lists five vehicles are at the scene.
The Wimmera Mail-Times believes the driver sustained minor injuries.
Police are investigating the cause of the rollover.